UK medical cannabis clinics

A guide to the licensed specialists who can prescribe medical cannabis in the UK. All clinics listed operate under GMC and relevant national regulator guidelines (CQC in England; Healthcare Improvement Scotland in Scotland; Healthcare Inspectorate Wales in Wales).

Important: CannaCheck does not recommend or endorse any specific clinic. All information is provided for guidance only. Always verify details directly with the clinic before booking.

Best Medical Cannabis Clinics UK 2026 — At a Glance

Nine specialist clinics are currently licensed to prescribe medical cannabis in the UK. Here is an objective summary of which clinic is best suited to different patient needs, based on publicly available information on fees, wait times, and clinical approach.

Lowest entry price
Releaf — from £79
App-based model, fast booking, lowest initial consultation fee of any UK clinic. Best for patients who want the lowest cost point of entry with a fully digital experience.
Fastest appointments
Lyphe Clinic — from £99, typically 1–3 working days
Largest UK clinic network with physical locations in London, Manchester, Birmingham, Leeds, Bristol, and Edinburgh. Best for patients who value fast access and the option of in-person appointments.
Most comprehensive assessment
Research-led, runs the UK Medical Cannabis Registry. Longest consultations (45–60 min). Best for neurological conditions, complex cases, paediatric epilepsy, and patients who want the most thorough specialist assessment.
Best for Universal Credit recipients
Alternaleaf — GAP Scheme (reduced fees)
The only UK cannabis clinic with a dedicated scheme for patients on Universal Credit and qualifying benefits. Reduced consultation and medication fees available. Apply before booking.
Weekend and evening appointments
Mamedica — from £95, 7-day service
Independent specialist clinic with a seven-day appointment model. Best for patients who need evening or weekend slots, or who have complex conditions requiring a more thorough specialist-led assessment.

Compare licensed UK medical cannabis clinics

Clinic First consultation Wait time Best for Model
Lyphe Clinic From £99 1–3 days Chronic pain, PTSD, anxiety — value + speed Online UK-wide Full review →
Releaf From £79 2–5 days Lowest initial fee, app-based journey Online only Full review →
Mamedica From £95 3–7 days Complex cases, 7-day appointment service Online UK-wide Full review →
Curaleaf Clinic From £100 3–7 days International group, broad formulary Online UK-wide Full review →
Sapphire Medical From £150 5–10 days Research registry, complex neurology, epilepsy Online UK-wide Full review →
Alternaleaf From £99 3–7 days Chronic pain, clear pricing, patient access Online only Full review →
Zerenia From £99 2–5 days Largest network, self-referral, in-person option Online + in-person Full review →
TMCC From £149 3–7 days Pioneer prescriber, chronic pain & PTSD Online only Full review →
London Cannabis Clinic From £299 5–10 days Harley Street, premium boutique, pain focus Online + in-person Full review →

First consultation prices and wait times are approximate. Verify directly with the clinic before booking.

Quick comparison
Clinic Initial fee Wait Best for
Lyphe From £99 1–3 days Largest network, broadest coverage
Releaf From £79 2–5 days Lowest initial fee, app-based
Mamedica From £95 3–7 days Complex cases, 7-day service
Curaleaf Clinic From £100 3–7 days International group, broad formulary
Sapphire Medical From £150 5–10 days Research registry, complex neuro
Alternaleaf From £99 3–7 days Accessibility, clear pricing
Zerenia From £99 2–5 days Large network, self-referral
TMCC From £149 3–7 days Pioneer prescriber, pain & PTSD
London Cannabis Clinic From £299 5–10 days Harley Street, boutique service

Prices and wait times are approximate and subject to change. Verify with the clinic directly before booking.

Lyphe UK's largest provider

Over 40,000 patients treated. Fast appointments, broad condition coverage, and a network of specialist doctors.

Consultation: From £99 Wait: 1–3 days
Releaf Fully online

End-to-end digital process. Upload your records, consult online, and receive your prescription within days.

Consultation: From £79 Wait: 2–5 days
Mamedica Specialist-led

Independent specialist clinic with a strong focus on complex and treatment-resistant cases. Seven-day-a-week appointments.

Consultation: From £95 Wait: 3–7 days
Curaleaf Clinic International expertise

Part of a global medical cannabis group. Wide product formulary, evidence-led prescribing.

Consultation: From £100 Wait: 3–7 days
Sapphire Medical Research-led

One of the UK's pioneering cannabis clinics. Operates the UK Medical Cannabis Registry for real-world evidence.

Consultation: From £150 Wait: 5–10 days
Alternaleaf Patient-focused

Formerly Integro Medical Clinics. Online-only service with clear pricing and a straightforward, accessible patient journey.

Consultation: From £99 Wait: 3–7 days
Zerenia Largest network

One of the UK's largest prescribing networks. Self-referral available. Broad condition coverage across multiple clinic locations.

Consultation: From £99 Wait: 2–5 days
TMCC Pioneer prescriber

One of the UK's original private cannabis prescribers. Specialist-led assessments for chronic pain, anxiety, and PTSD.

Consultation: From £149 Wait: 3–7 days
London Cannabis Clinic Harley Street

Boutique specialist clinic on Harley Street. Emphasis on comprehensive pain assessments and personalised care plans.

Consultation: From £299 Wait: 5–10 days

Prices and wait times are indicative and subject to change. Always check directly with the clinic.

How to choose the right clinic

Check your condition is covered

Not every clinic covers every condition. Check the clinic's list of treatable conditions before booking to avoid a wasted consultation fee.

Ask about their formulary

UK clinics can only prescribe Schedule 2 cannabis medicines. The range of products available varies by clinic — some have broader formularies than others.

Understand the ongoing cost

The initial consultation is just the start. Budget for monthly follow-ups (typically £50–£100) and prescription medicine costs (£150–£400/month depending on product).

Verify GMC specialist register listing

All prescribing doctors must be on the GMC specialist register — this is the legal requirement for any UK cannabis prescription. Any reputable clinic will confirm this directly. Check the GMC register →

Read patient reviews

Trustpilot and Google Reviews can give real-world insight into wait times, customer service, and renewal processes — which matter as much as the initial consultation.

Check if you qualify first

Our free eligibility checker takes under two minutes. Find out whether you are likely to qualify before spending money on a consultation.

No registration required. For information only.

See how the prescription process works →

How to find the best UK medical cannabis clinic for your condition

There is no single "best" UK cannabis clinic — the right choice depends on your specific condition, medical history, budget, and priorities. Here is how to approach the decision:

By condition

Chronic pain and PTSD: These are the most common qualifying conditions and all nine clinics above cover them. For chronic pain patients, Lyphe and Releaf offer the fastest and most cost-competitive access. For patients with complex, treatment-resistant pain (CRPS, neuropathic pain with multiple failed agents), Mamedica and Sapphire Medical offer more thorough assessments.

Epilepsy: Sapphire Medical is the most clinically credentialled option for epilepsy patients, including rare paediatric syndromes. TMCC also has experience in this area. Most other clinics do not cover paediatric epilepsy.

ADHD: ADHD prescribing requires strong documentation of failed conventional treatments (methylphenidate, lisdexamfetamine). Not all clinics accept ADHD as a primary indication — check directly before booking. See our full ADHD medical cannabis guide.

MS: Multiple sclerosis spasticity is covered by most clinics, including prescribing of Sativex (nabiximols) at some. Sapphire has particular experience with neurological MS presentations.

Endometriosis and women's health: Increasingly recognised by UK cannabis prescribers. Check individual clinic eligibility — not all list endometriosis explicitly.

By budget

Initial consultation fees range from £79 (Releaf) to £299 (London Cannabis Clinic). However, the initial fee is only one component of the ongoing cost. Monthly medication typically costs £100 to £400 per month regardless of clinic, and follow-up appointments (usually monthly for the first six months) are £45 to £100 each. A full year of treatment can cost £2,000 to £5,000+ including all components. See the complete medical cannabis cost guide for a full breakdown.

Online-only vs clinics with physical locations

The majority of UK cannabis clinics operate exclusively online — consultations via secure video call from home. Only Zerenia and London Cannabis Clinic offer significant in-person clinic options. For most patients, the online model works well. In-person appointments may be preferable for patients who struggle with video technology or who have complex presentations requiring physical examination.

What is the waiting time to get a UK medical cannabis prescription?

From initial booking to first prescription, typical timeframes range from one week (Releaf, Lyphe for straightforward cases) to two to four weeks (Sapphire Medical, London Cannabis Clinic where assessments are more comprehensive). Medication delivery from a licensed UK pharmacy adds a further two to five working days after the prescription is issued.

Frequently asked questions — UK medical cannabis clinics

Do I need a GP referral to access a UK cannabis clinic?
No. All nine clinics above accept self-referral — patients can book directly without a GP referral. However, having a GP summary letter, specialist letters, and medical records significantly strengthens your application and reduces the likelihood of a failed consultation.
Are UK medical cannabis clinics regulated?
All prescribing clinicians must be on the GMC specialist register — this is a legal requirement under the Misuse of Drugs Regulations 2001 (Schedule 2). In England, the clinic itself may be CQC-registered. You can verify any clinician at gmc-uk.org before or after your appointment.
Which UK cannabis clinic has the lowest initial fee?
Releaf currently offers the lowest initial consultation fee at from £79. Lyphe, Zerenia, and Alternaleaf start from £99. Remember that the initial fee is only one component — monthly medication costs are the same across clinics as they are paid directly to the pharmacy.
Can I switch clinics if I am unhappy with my current prescriber?
Yes. Transferring between UK cannabis clinics is possible, though a new clinical assessment is typically required by the receiving clinic. Bring your full medical and treatment history when switching. Continuity of your prescription during transfer is not guaranteed — discuss the process with both clinics before moving.
What conditions do UK cannabis clinics treat?
The most commonly treated conditions at UK cannabis clinics are chronic pain, PTSD, anxiety disorders, sleep disorders, fibromyalgia, multiple sclerosis, epilepsy, and cancer-related symptoms. Some clinics also cover ADHD, endometriosis, Tourette syndrome, and rare neurological conditions. See the full conditions guide for detailed information on each.

Last reviewed: June 2026. CannaCheck is an independent information resource with no commercial relationship with any clinic listed. Prices and wait times are subject to change — always verify directly with the clinic.